"Injini Yezempilo"——BlackGinol™
Ukuhlala unganyakazi emsebenzini isikhathi eside, akugcini nje ngokubonakala kwesisu kuphela, kodwa futhi amehlo abe mnyama uma usukuma ngezikhathi ezithile ... Zonke izimpawu zibonisa ukuthi izinkinga zempilo azisekho "ilungelo lobunikazi" yasebekhulile. Indlela yokuthuthukisa ngokuphepha nangempumelelo izinkinga zezempilo isiphenduke into egxilwa kakhulu kubantu bayo yonke iminyaka.
Kukhona imifino "engaveli" kuphela kakhulu emikhiqizweni yokuncipha kwesisindo yaseJapan engxenyeni yokuqala ka-2023, kodwa futhi iye yasetshenziswa abantu baseNingizimu-mpumalanga ye-Asia amakhulu eminyaka ukuthuthukisa ikhono lokugijima, ukuthuthukisa amandla, kanye nokukhulula i-allergies[1, 2]. Ijinja emnyama, ebizwa ngokuthi "i-ginseng yase-Thai" e-Thailand futhi ikhiqizwa kakhulu eNingizimu-mpumalanga ye-Asia[3]. I-BlackGinol™ (I-Black Ginger Extract evela ku-BioGin) ayikwazi nje kuphela ukusheshisa i-metabolism yamandla futhi ikhuthaze ukushiswa kwamafutha, kodwa futhi ithuthukise ukukhuthazela kokuzivocavoca futhi inciphise ukukhathala.
Umdwebo1. I-Rhizome, imifino, nembali ye-BlackGinol™
Lungiselela ukusebenza komzimba: thuthukisa ikhono lokusubatha futhi uthuthukise impilo nokuqina
Njengoba abantu bekhula, ukuqina kwabo ngokomzimba okuhlobene nempilo kuzokwehla kancane kancane, okungase kuhlobane nokulimala kwe-oxidative okubangelwa ama-radicals mahhala [4]. Ukudla kwansuku zonke kwamazinga aphezulu e-antioxidants kungakhuthaza ukuthuthukiswa kwamandla emisipha yamathambo [5]. IBlackGinol™ ingathuthukisa kakhulu impilo yomzimba ngomthamo wayo we-antioxidant. Wattanathorn et al. [I-6] ithole ukuthi ukuthatha i-90 mg ye-ginger emnyama ekhishwe nsuku zonke amaviki e-8 kubonise ukuthuthukiswa okuphawulekayo kumthamo wokuzivocavoca, amandla emisipha yemilenze ephansi kanye nokukhuthazela kwe-aerobic, kanye nokuthuthukisa kakhulu umthamo we-antioxidant womzimba (Ithebula 1, Umfanekiso 2).
Ithebula 1: Umphumela weK. parviflorangokufaneleka ngokomzimba okuhlobene nempilo | ||||
Amapharamitha akaliwe | Iqembu | Umthamo wangaphambili | Inyanga engu-1 | 2 izinyanga |
Ukuhlolwa kwesitulo sesihlalo semizuzwana engama-30. (isekhondi) | I-Placebo | 19.13 + 2.79 | 19.26 + 1.43 | 18.93 + 1.70 |
KP90 | 18.6+2.52 | 19.6+2.13 | 20.66 + 2.28# | |
6 imiz. isivivinyo sokuhamba (m.) | I-Placebo | 567.33 + 33.52 | 598.73 + 31.57 | 571.26 + 32.05 |
KP90 | 572.8 + 32.65 | 575.46 + 34.29 | 601.26 + 33.70∗# | |
Idatha yayikhona njengesilinganiso esingu-± SEM (n = 15/group). ∗P value |
Umdwebo 2. Umthelela we-KP ezingeni le-SOD(A), i-CAT (B) , i-GSH-Px (C) ne-MDA (D) ku-serum.
Izifinyezo: KP,I-Kaempferia parviflora
Ngakho-ke, iBlackGinol™ ingathuthukisa ukuqina komzimba ngokunciphisa ingcindezi ye-oxidative futhi ingasetshenziswa njengesithasiselo sezempilo ukuthuthukisa ukuqina komzimba. Ingathuthukisa ngempumelelo amandla omzimba we-antioxidant, ilawule i-metabolism yamandla, futhi ithuthukise ukukhuthazela kwe-aerobic namandla emisipha. Indlela yokusebenza iboniswa kuMfanekiso 3.
Umdwebo 3. Umdwebo wohlelo ubonise isenzo esingaba khona se-BlackGinol™ emandleni emisipha yamaphethelo aphansi kanye nokukhuthazela kwe-aerobic.
Dala umzimba onempilo: ukwandisa ukusetshenziswa kwamandla futhi unciphise indawo yamafutha
IBlackGinol™ inenye inzuzo ngoba ingalawula futhi ikhuthaze i-metabolism yamandla. Isithako esisiginesha se-BlackGinol™ 5,7-dimethoxyflavone, singasheshisa imetabolism kanye nokujikeleza kwegazi, ngaleyo ndlela kudle amandla, ikakhulukazi amafutha esisu (amafutha e-visceral namafutha angaphansi kwesikhumba). Lokhu kuboniswe ucwaningo luka-Yoshino S et al. [14] (Umfanekiso 4).
Fig4. Izinguquko endaweni yamafutha esiswini ngemva kokuthatha ukudla okuhlola nsuku zonke.
Izifinyezo: I-SFA, indawo yamafutha e-subcutaneous; I-TFA, indawo ephelele yamafutha; I-VFA, indawo yamafutha e-visceral.
Kodwa-ke, ucwaningo luye lwabonisa ukuthi okuqukethwe kwe-flavonoids emnyama ye-turmeric evela emisuka ehlukene kuyahluka kakhulu. Njengokudla kwezempilo, okuqukethwe okujwayelekile kwe-5,7-dimethylflavone ku-ginger rhizome extract akumele kube ngaphansi kuka-2.5%.
Umdwebo 5.I-Kaempferia parviflora kanye nokukhishwa kwayoI-BlackGinol™
I-BioGin Health ingahlinzeka amakhasimende nge-BlackGinol™ ngokuqukethwe okuhlukile kwe-5,7-dimethoxyflavonoids. Izinto zokusetshenziswa zivela emapulazini emvelo eThailand atshala ujinja omnyama, futhi ikhwalithi yomkhiqizo ilawulwa ngokuqinile ukusuka emthonjeni. Uhla olugcwele lwezixazululo zemikhiqizo yezempilo lwe-BioGin Health lukhiqizwa kusetshenziswa izinkundla zobuchwepheshe ezintathu ezinkulu: i-MSET®isitshalo-based, SOB/SET® isitshalo-basedkanye ne-BtBLlife® isitshalo-based . Izinto zokusetshenziswa ezisetshenziswa zisebenzisa ngokuqinile inqubo ye-multi-step identification (ID) - okuhlanganisa inhlanganisela yezinqubo ezimbili noma ngaphezulu zokuhlaziya izithenjwa. Ngesikhathi esifanayo, sinokubambisana kwesikhathi eside nezinkampani zangaphandle ezizimele eziqashelwa emhlabeni wonke, njenge-NSF, i-Eurofins, i-Chroma Dax kanye ne-China Food and Drug Administration, futhi imikhiqizo yethu inemibiko yokuhlola yangaphandle ephelele. Yonke imikhiqizo iyalandeleka, iyasimama, iyaqinisekiswa, futhi nekhwalithi iqinisekisiwe!
Izithenjwa:
[[1]] SAOKAEW S, WILAIRAT P, RAKTANYAKAN P, et al. Imiphumela yomtholampilo ye-Krachaidum (Kaempferia parviflora): Ukubuyekezwa okuhlelekile [J]. J Evid-Based Compl Alt Med, 2017, 22(3): 413–428. doi: 10.1177/ 2156587216669628.
[2] PICHEANSOONTHON C, KOONTER S. Amanothi ohlotsheni lwe-Kaempferia L. (Zingiberaceae) e-Thailand [J]. J Thai Trad Altern Med, 2008, 6(1): 73–93.
[3] KOBAYASHI H, SUZUKI R, SATO K, et al. Umthelela we-Kaempferia parviflora extract ku-knee osteoarthritis [J]. J Nat Med, 2018, 72(1): 136–144. doi: 10.1007/s11418-017-1121-6.
[4] M. De la Fuente, "Imiphumela yama-antioxidants ku-immune systemageing," i-European Journal of Clinical Nutrition, vol. 56, no. 3, pp. I-S5–S8, 2002.
[5] M. Cesari, M. Pahor, B. Bartali et al., “Ama-Antioxidants nokusebenza komzimba kubantu asebekhulile: ucwaningo lwe-Invecchiare in Chianti(InCHIANTI),” American Journal of Clinical Nutrition,vol. 79, nxa. 2, amakhasi 289-294, 2004.
[6] WATTANATHORN J, MUCHIMAPURA S, TONG-UN T, et al. Umphumela omuhle wokuguquguquka wokusetshenziswa kwamaviki angu-8 kwe-Kaempferia parviflora ekuqineni ngokomzimba okuhlobene nempilo kanye nesimo se-oxidative kumavolontiya anempilo akhulile [J]. I-Evid Based Complement Alternat Med, 2012, 2012: 732816. doi: 10.1155/2012/732816.